Liverpool continued their dismal run with their third Premier League defeat of the season when they welcomed Burnley.
Ashley Barnes scored the only goal from the penalty spot after seven minutes of time Reds Saw them 68 matches unbeaten in the domestic league ended in a fatal 1-0 defeat on Thursday.
The Premier League and the world champions have now made a quick turnaround before they head to Manchester United on Sunday to face the fourth round of the FA Cup.
Here, we look forward to the changes Jurgen Klopp He can achieve it when his team is next on the job.
While Liverpool were surprisingly strong against Aston Villa in the final round – despite the Midlanders introducing the Under-23 team – the back streak was almost completely round.
That may be the same again, although Klopp has more options, not least at left-back as Costas Tsimikas was on the bench Thursday as a cover for Andy Robertson. James Milner is also another competitor, but he may be wanted in midfield.
Nico Williams could replace Trent Alexander-Arnold on the flank with the England player out of form.
Nat Phillips and Reese Williams are both options at the center of the defense, although at least one of Fabinho and Joel Matip could continue as the center back. Jordan Henderson, if appropriate, is another alternative.
Thiago or not?
The midfield will, as always, be a key area in such gigantic conflicts between the two northwestern rivals.
Klopp could choose to substitute the three who started against Burnley – Jenny Vinaldom, Thiago Alcantara and Alex Oxlade Chamberlain.
Milner and Curtis Jones haven’t seen much time in the match since the Villa match and will be ready to attend.
Naby Keita stays out while there are doubts about Henderson.
Xherdan Shaqiri could drop into the midfield role he played against United last weekend, although there is room for a tactical adjustment to give Thiago more freedom to advance.
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Liverpool’s surprise attack against Burnley opened the door to a very direct exchange between the top three.
Mohamed Salah, Roberto Firmino and Takumi Minamino all came off the bench against Claret and will be hoping to start at Old Trafford.
Sadio Mane may be taking advantage of his breath, while Divock Origi missed Liverpool’s best chance to end a drought in scoring goals in the Premier League on Thursday.